具有CTL免疫反应的HTLV-I感染模型的全局稳定性(英文)--《数学季刊...

来自 : www.cnki.com.cn/Article/CJFDTo 发布时间：2021-03-24

宋强 【摘要】：In this paper, a mathematical model for HTLV-I infection of CD4+ T cells that incorporates the CD8+ cytotoxic T-cell(CTL) response is studied. We establish two threshold parameters R0 and R1, the basic reproduction numbers for viral persistence and for CTL response, respectively. We also show that the parameter R1 can be used to distinguish asymptomatic carriers from HAM/TSP patients and as an important control parameter for preventing the development of HAM/TSP.
2013年4月1日【摘要】:In this paper, a mathematical model for HTLV-I infection of CD4+ T cells that incorporates the CD8+ cytotoxic T-cell(CTL) response ...CTL response HTLV-I infection global stability Lyapunov functionCTL response HTLV-I infection global stability Lyapunov function具有CTL免疫反应的HTLV